Genes identified by TWAS
References
TWAS is another powerful integrative analysis approach and aimed at identifying bipolar disorder risk genes whose expression perturbations may confer disease susceptibility by integrating GWAS summary statistics and expression quantitative trait loci (eQTL) data.
| TWAS | - Integrative approaches for large-scale transcriptome-wide association studies. Nature Genetics, 48(3):245-52. [PMID: 26854917] |
| PGC3 GWAS | - Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics, 53(6):817-829. [PMID: 34002096] |
| PGC2 GWAS | - Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics, 51(5):793-803. [PMID: 31043756] |
| CMC eQTL | - Gene expression elucidates functional impact of polygenic risk for schizophrenia. Nature Neuroscience, 19(11):1442-1453. [ PMID: 27668389] |
| LIBD2-DLPFC eQTL | - Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia. Neuron,103(2):203-216.e8. [PMID: 31174959] |
| PsychEncode eQTL | - Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder. Science, 362(6420):eaat8127. [PMID: 30545856]) |
If you used the integrative analysis result in this database, please cite the relative references.