In 2021, the Bipolar disorder Working Group of the Psychiatric Genomics Consortium (PGC) reported a new performed a genome-wide association study (PGC3 GWAS) of 41,917 bipolar disorder cases and 371,549 controls of European descent, which identified 64 associated genomic loci. In this study, of the 64 genome-wide significant loci, 33 are novel discoveries (ie. loci not overlapping with any locus previously reported as genome-wide significant for bipolar disorder). (Mullins et al. Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics, 53(6):817-829. [PMID: 34002096]).